BAIT
CLIP2
CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4
CAP-GLY domain containing linker protein 2
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
CLASP1
1700030C23Rik, 5730583A19Rik, B130045P17Rik, CLASP1alpha
CLIP associating protein 1
GO Process (10)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- cell division [ISO]
- establishment of spindle orientation [ISO]
- exit from mitosis [ISO]
- microtubule anchoring [ISO]
- microtubule bundle formation [ISO]
- microtubule cytoskeleton organization [ISO]
- microtubule nucleation [ISO]
- microtubule organizing center organization [ISO]
- negative regulation of microtubule depolymerization [IDA, ISO]
- negative regulation of microtubule polymerization or depolymerization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.
CLIP-170 and CLIP-115 are cytoplasmic linker proteins that associate specifically with the ends of growing microtubules and may act as anti-catastrophe factors. Here, we have isolated two CLIP-associated proteins (CLASPs), which are homologous to the Drosophila Orbit/Mast microtubule-associated protein. CLASPs bind CLIPs and microtubules, colocalize with the CLIPs at microtubule distal ends, and have microtubule-stabilizing effects in transfected cells. After ... [more]
Cell Mar. 23, 2001; 104(6);923-35 [Pubmed: 11290329]
Throughput
- Low Throughput
Additional Notes
- Figure 3D
Curated By
- BioGRID