BAIT
IL16
mKIAA4048
interleukin 16
GO Process (2)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
KCNJ2
IRK1, Kcnf1, Kir2.1, RP23-408D5.1
potassium inwardly-rectifying channel, subfamily J, member 2
GO Process (17)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- cardiac muscle cell action potential [IMP]
- cardiac muscle cell action potential involved in contraction [ISO]
- magnesium ion transport [IDA]
- membrane repolarization during action potential [ISO]
- membrane repolarization during cardiac muscle cell action potential [ISO]
- positive regulation of potassium ion transmembrane transport [ISO]
- potassium ion import [IBA, ISO]
- potassium ion transmembrane transport [ISO]
- potassium ion transport [ISO]
- protein homotetramerization [ISO]
- regulation of cardiac muscle cell contraction [ISO]
- regulation of heart rate by cardiac conduction [ISO]
- regulation of ion transmembrane transport [IBA]
- regulation of membrane repolarization [ISO]
- regulation of skeletal muscle contraction via regulation of action potential [ISO]
- relaxation of cardiac muscle [ISO]
- relaxation of skeletal muscle [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- T-tubule [ISO]
- dendrite [ISO]
- dendritic spine [ISO]
- integral component of plasma membrane [IBA]
- intercalated disc [ISO]
- intrinsic component of membrane [ISO]
- neuronal cell body [ISO]
- plasma membrane [ISO]
- rough endoplasmic reticulum [ISO]
- smooth endoplasmic reticulum [ISO]
- voltage-gated potassium channel complex [ISO]
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.
Interleukin (IL)-16 is a proinflammatory cytokine that has attracted widespread attention because of its ability to block HIV replication. We describe the identification and characterization of a large neuronal IL-16 precursor, NIL-16. The N-terminal half of NIL-16 constitutes a novel PDZ domain protein sequence, whereas the C terminus is identical with splenocyte-derived mouse pro-IL-16. IL-16 has been characterized only in ... [more]
J. Neurosci. Sep. 15, 1999; 19(18);7770-80 [Pubmed: 10479680]
Throughput
- Low Throughput
Curated By
- BioGRID