BAIT
GRIN2D
GluN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GO Process (11)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- adult locomotory behavior [ISO]
- cation transmembrane transport [IDA]
- cation transport [IDA]
- detection of mechanical stimulus involved in sensory perception of pain [ISO]
- ion transmembrane transport [IBA, ISO]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO]
- regulation of excitatory postsynaptic membrane potential [ISO]
- regulation of ion transmembrane transport [IMP]
- regulation of sensory perception of pain [ISO]
- startle response [ISO]
- synaptic transmission, glutamatergic [IMP]
Gene Ontology Molecular Function- N-methyl-D-aspartate selective glutamate receptor activity [IDA, IMP, ISO]
- cation channel activity [IDA]
- extracellular-glutamate-gated ion channel activity [IBA]
- glutamate binding [IMP]
- ionotropic glutamate receptor activity [IDA]
- neurotransmitter binding [IMP]
- protein binding [IPI]
- voltage-gated cation channel activity [IMP]
- N-methyl-D-aspartate selective glutamate receptor activity [IDA, IMP, ISO]
- cation channel activity [IDA]
- extracellular-glutamate-gated ion channel activity [IBA]
- glutamate binding [IMP]
- ionotropic glutamate receptor activity [IDA]
- neurotransmitter binding [IMP]
- protein binding [IPI]
- voltage-gated cation channel activity [IMP]
Gene Ontology Cellular Component
Rattus norvegicus
PREY
IL16
mKIAA4048
interleukin 16
GO Process (2)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.
Interleukin (IL)-16 is a proinflammatory cytokine that has attracted widespread attention because of its ability to block HIV replication. We describe the identification and characterization of a large neuronal IL-16 precursor, NIL-16. The N-terminal half of NIL-16 constitutes a novel PDZ domain protein sequence, whereas the C terminus is identical with splenocyte-derived mouse pro-IL-16. IL-16 has been characterized only in ... [more]
J. Neurosci. Sep. 15, 1999; 19(18);7770-80 [Pubmed: 10479680]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| IL16 GRIN2D | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID