BAIT

NOS1AP

6330408P19Rik, CAPON
nitric oxide synthase 1 (neuronal) adaptor protein
Alzheimer's Disease Project
GO Process (3)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

NHP2

DKCB2, NHP2P, NOLA2, HSPC286
NHP2 ribonucleoprotein
GO Process (1)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Phospho-tyrosine dependent protein-protein interaction network.

Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U

Post-translational protein modifications, such as tyrosine phosphorylation, regulate protein-protein interactions (PPIs) critical for signal processing and cellular phenotypes. We extended an established yeast two-hybrid system employing human protein kinases for the analyses of phospho-tyrosine (pY)-dependent PPIs in a direct experimental, large-scale approach. We identified 292 mostly novel pY-dependent PPIs which showed high specificity with respect to kinases and interacting proteins ... [more]

Mol. Syst. Biol. Mar. 01, 2015; 11(3);794 [Pubmed: 25814554]

Throughput

  • High Throughput

Curated By

  • BioGRID