BAIT
RALA
RAL
v-ral simian leukemia viral oncogene homolog A (ras related)
GO Process (10)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- Ras protein signal transduction [TAS]
- actin cytoskeleton reorganization [IDA]
- chemotaxis [TAS]
- cytokinesis [IDA]
- membrane organization [TAS]
- membrane raft localization [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of filopodium assembly [IDA]
- regulation of exocytosis [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GLS2
GA, GLS, LGA, hLGA
glutaminase 2 (liver, mitochondrial)
GO Process (9)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- cellular amino acid biosynthetic process [TAS]
- cellular amino acid metabolic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- glutamate secretion [TAS]
- neurotransmitter secretion [TAS]
- reactive oxygen species metabolic process [IMP]
- regulation of apoptotic process [IMP]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.
Interferon alpha (IFNalpha) has significant clinical activity in the treatment of patients with chronic myelogenous leukaemia (CML), but the mechanisms of its selective efficacy in the treatment of the disease are unknown. The CrkL adaptor protein interacts directly with the BCR-ABL fusion protein that causes the malignant transformation and is constitutively phosphorylated in BCR-ABL-expressing cells. In the present study, we ... [more]
Br. J. Haematol. Feb. 01, 2001; 112(2);327-36 [Pubmed: 11167825]
Throughput
- Low Throughput
Curated By
- BioGRID