BAIT
PTPN1
PTP1B
protein tyrosine phosphatase, non-receptor type 1
GO Process (19)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- JAK-STAT cascade involved in growth hormone signaling pathway [TAS]
- actin cytoskeleton reorganization [IMP]
- blood coagulation [TAS]
- cytokine-mediated signaling pathway [TAS]
- endoplasmic reticulum unfolded protein response [IDA]
- interferon-gamma-mediated signaling pathway [TAS]
- negative regulation of ERK1 and ERK2 cascade [ISS]
- negative regulation of insulin receptor signaling pathway [NAS]
- negative regulation of vascular endothelial growth factor receptor signaling pathway [ISS]
- peptidyl-tyrosine dephosphorylation [IDA, IMP]
- peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [ISS]
- platelet activation [TAS]
- platelet-derived growth factor receptor-beta signaling pathway [IMP]
- regulation of endocytosis [IDA]
- regulation of hepatocyte growth factor receptor signaling pathway [IMP]
- regulation of interferon-gamma-mediated signaling pathway [TAS]
- regulation of signal transduction [IMP]
- regulation of type I interferon-mediated signaling pathway [TAS]
- type I interferon signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MRC2
CD280, CLEC13E, ENDO180, UPARAP
mannose receptor, C type 2
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Systematic identification of molecular links between core and candidate genes in breast cancer.
Despite the remarkable progress achieved in the identification of specific genes involved in breast cancer (BC), our understanding of their complex functioning is still limited. In this manuscript, we systematically explore the existence of direct physical interactions between the products of BC core and associated genes. Our aim is to generate a protein interaction network of BC-associated gene products and ... [more]
J. Mol. Biol. Mar. 27, 2015; 427(6);1436-50 [Pubmed: 25640309]
Throughput
- High Throughput
Curated By
- BioGRID