BAIT

KLK13

KLK-L4, KLKL4
kallikrein-related peptidase 13
GO Process (1)
GO Function (3)
GO Component (4)

Gene Ontology Biological Process

Homo sapiens

Reconstituted Complex

An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.

Publication

Complex formation between human kallikrein 13 and serum protease inhibitors.

Kapadia C, Yousef GM, Mellati AA, Magklara A, Wasney GA, Diamandis EP

BACKGROUND: The kallikrein family is a group of 15 serine protease genes clustered on chromosome 19q13.4. Human kallikrein gene 13 (KLK13) is a member of this family and encodes for a trypsin-like, secreted serine protease (hK13). Given that other kallikreins are sequestered by serum protease inhibitors, we hypothesized that hK13 may also interact with similar inhibitors. Our objective was to ... [more]

Clin. Chim. Acta Jan. 01, 2004; 339(1);157-67 [Pubmed: 14687906]

Throughput

  • Low Throughput

Curated By

  • BioGRID