BAIT
PLEKHG5
BC023181, Syx, RP23-284C20.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
GO Process (5)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ACTG1
AL023024, Actg, Actl, E51, RP23-82I5.1
actin, gamma, cytoplasmic 1
GO Process (2)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.
Controlled regulation of Rho GTPase activity is an essential component mediating growth factor-stimulated migration. We have previously shown that angiomotin (Amot), a membrane-associated scaffold protein, plays a critical role during vascular patterning and endothelial migration during embryogenesis. However, the signaling pathways by which Amot controls directional migration are not known. Here we have used peptide pull-down and yeast 2-hybrid (Y2H) ... [more]
Blood Jan. 01, 2009; 113(1);244-53 [Pubmed: 18824598]
Throughput
- Low Throughput
Additional Notes
- Syx peptides were used in the experiment.
Curated By
- BioGRID