AHI1
Gene Ontology Biological Process
- Kupffer's vesicle development [ISS]
- cellular protein localization [ISS]
- central nervous system development [ISS]
- cilium assembly [ISS]
- cilium morphogenesis [ISS]
- cloaca development [ISS]
- heart looping [ISS]
- hindbrain development [ISS]
- left/right axis specification [ISS]
- morphogenesis of a polarized epithelium [ISS]
- negative regulation of apoptotic process [ISS]
- otic vesicle development [ISS]
- photoreceptor cell outer segment organization [ISS]
- positive regulation of polarized epithelial cell differentiation [ISS]
- positive regulation of receptor internalization [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- pronephric duct morphogenesis [ISS]
- pronephric nephron tubule morphogenesis [ISS]
- regulation of behavior [ISS]
- retina layer formation [ISS]
- specification of axis polarity [ISS]
- transmembrane receptor protein tyrosine kinase signaling pathway [ISS]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
OFD1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| AHI1 OFD1 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | - | BioGRID | 1430060 |
Curated By
- BioGRID