BAIT
CEP290
3H11Ag, BBS14, CT87, JBTS5, LCA10, MKS4, NPHP6, POC3, SLSN6, rd16
centrosomal protein 290kDa
GO Process (12)
GO Function (2)
GO Component (10)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- cilium assembly [ISS]
- cilium morphogenesis [ISS]
- eye photoreceptor cell development [ISS]
- hindbrain development [ISS]
- mitotic cell cycle [TAS]
- otic vesicle formation [ISS]
- positive regulation of intracellular protein transport [IMP]
- positive regulation of transcription, DNA-templated [IDA]
- pronephros development [ISS]
- protein transport [ISS]
- regulation of establishment of protein localization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PGD
6PGD
phosphogluconate dehydrogenase
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Curated By
- BioGRID