BAIT
PCM1
PTC4
pericentriolar material 1
GO Process (11)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- centrosome organization [IMP]
- cilium assembly [IMP]
- cytoplasmic microtubule organization [IMP]
- interkinetic nuclear migration [ISS]
- intraciliary transport involved in cilium morphogenesis [IMP]
- microtubule anchoring [ISS]
- mitotic cell cycle [TAS]
- negative regulation of neurogenesis [ISS]
- positive regulation of intracellular protein transport [IMP]
- protein localization to centrosome [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KCTD12
C13orf2, PFET1, PFETIN
potassium channel tetramerization domain containing 12
GO Process (0)
GO Function (1)
GO Component (1)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Curated By
- BioGRID