BAIT
AHI1
AHI-1, JBTS3, ORF1, dJ71N10.1, RP1-32B1.2
Abelson helper integration site 1
GO Process (23)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
- Kupffer's vesicle development [ISS]
- cellular protein localization [ISS]
- central nervous system development [ISS]
- cilium assembly [ISS]
- cilium morphogenesis [ISS]
- cloaca development [ISS]
- heart looping [ISS]
- hindbrain development [ISS]
- left/right axis specification [ISS]
- morphogenesis of a polarized epithelium [ISS]
- negative regulation of apoptotic process [ISS]
- otic vesicle development [ISS]
- photoreceptor cell outer segment organization [ISS]
- positive regulation of polarized epithelial cell differentiation [ISS]
- positive regulation of receptor internalization [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- pronephric duct morphogenesis [ISS]
- pronephric nephron tubule morphogenesis [ISS]
- regulation of behavior [ISS]
- retina layer formation [ISS]
- specification of axis polarity [ISS]
- transmembrane receptor protein tyrosine kinase signaling pathway [ISS]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DSP
DCWHKTA, DP, DPI, DPII
desmoplakin
GO Process (12)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- apoptotic process [TAS]
- bundle of His cell to Purkinje myocyte communication [IMP]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- desmosome organization [ISS]
- epidermis development [TAS]
- intermediate filament organization [ISS]
- keratinocyte differentiation [IDA]
- peptide cross-linking [IDA]
- protein localization to adherens junction [ISS]
- regulation of heart rate by cardiac conduction [IMP]
- ventricular cardiac muscle cell action potential [IMP]
- ventricular compact myocardium morphogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID