BAIT
CNTRL
CEP1, CEP110, FAN, bA165P4.1, RP11-165P4.1
centriolin
GO Process (2)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
SORBS1
CAP, FLAF2, R85FL, SH3D5, SH3P12, SORB1, RP11-476E15.1
sorbin and SH3 domain containing 1
GO Process (12)
GO Function (5)
GO Component (13)
Gene Ontology Biological Process
- cell-matrix adhesion [TAS]
- cellular response to insulin stimulus [ISS]
- focal adhesion assembly [ISS]
- glucose transport [ISS]
- insulin receptor signaling pathway [ISS]
- muscle contraction [TAS]
- positive regulation of establishment of protein localization to plasma membrane [ISS]
- positive regulation of glucose import [ISS]
- positive regulation of glycogen biosynthetic process [ISS]
- positive regulation of lipid biosynthetic process [ISS]
- positive regulation of signal transduction [IC, ISS]
- stress fiber assembly [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID