BAIT
CNTRL
CEP1, CEP110, FAN, bA165P4.1, RP11-165P4.1
centriolin
GO Process (2)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
RAB11B
H-YPT3
RAB11B, member RAS oncogene family
GO Process (15)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- Rab protein signal transduction [IBA]
- cellular response to acidic pH [IDA]
- constitutive secretory pathway [IMP]
- establishment of protein localization to membrane [IMP]
- insulin secretion involved in cellular response to glucose stimulus [ISS]
- intracellular protein transport [IBA]
- melanosome transport [IBA, ISS]
- receptor recycling [ISS]
- regulated secretory pathway [IBA, ISS]
- regulation of anion transport [IMP]
- regulation of endocytic recycling [ISS]
- regulation of protein localization to cell surface [IMP]
- retrograde transport, endosome to plasma membrane [IMP]
- transferrin transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID