BAIT
DYNLT1
CW-1, TCTEL1, tctex-1, RP11-114M11.1
dynein, light chain, Tctex-type 1
GO Process (4)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ADD1
ADDA, RP11-520M5.1
adducin 1 (alpha)
GO Process (9)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- actin cytoskeleton organization [IC]
- actin filament bundle assembly [IDA]
- activation of signaling protein activity involved in unfolded protein response [TAS]
- apoptotic process [TAS]
- barbed-end actin filament capping [IDA]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cellular protein metabolic process [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- positive regulation of protein binding [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID