BAIT
STIL
MCPH7, SIL, RP1-18D14.8
SCL/TAL1 interrupting locus
GO Process (16)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- cell proliferation [TAS]
- centrosome duplication [IDA, IMP]
- determination of left/right symmetry [ISS]
- embryonic axis specification [ISS]
- floor plate development [ISS]
- forebrain development [ISS]
- heart looping [ISS]
- in utero embryonic development [ISS]
- mitotic spindle organization [IMP]
- multicellular organism growth [ISS]
- negative regulation of apoptotic process [ISS]
- neural tube closure [ISS]
- neural tube development [ISS]
- notochord development [ISS]
- protein localization to centrosome [IMP]
- smoothened signaling pathway [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
FKBP4
FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase, p52
FK506 binding protein 4, 59kDa
GO Process (5)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID