BAIT
STIL
MCPH7, SIL, RP1-18D14.8
SCL/TAL1 interrupting locus
GO Process (16)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- cell proliferation [TAS]
- centrosome duplication [IDA, IMP]
- determination of left/right symmetry [ISS]
- embryonic axis specification [ISS]
- floor plate development [ISS]
- forebrain development [ISS]
- heart looping [ISS]
- in utero embryonic development [ISS]
- mitotic spindle organization [IMP]
- multicellular organism growth [ISS]
- negative regulation of apoptotic process [ISS]
- neural tube closure [ISS]
- neural tube development [ISS]
- notochord development [ISS]
- protein localization to centrosome [IMP]
- smoothened signaling pathway [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
VCPIP1
DUBA3, VCIP135
valosin containing protein (p97)/p47 complex interacting protein 1
GO Process (3)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID