BAIT
TMEM17
transmembrane protein 17
GO Process (2)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
ATP7A
DSMAX, MK, MNK, SMAX3, RP3-465G10.1
ATPase, Cu++ transporting, alpha polypeptide
GO Process (38)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
- T-helper cell differentiation [ISS]
- blood vessel development [ISS]
- blood vessel remodeling [ISS]
- cartilage development [ISS]
- catecholamine metabolic process [ISS]
- cellular copper ion homeostasis [IMP]
- central nervous system neuron development [ISS]
- cerebellar Purkinje cell differentiation [ISS]
- collagen fibril organization [ISS]
- copper ion export [ISS]
- copper ion import [ISS]
- copper ion transport [IMP]
- detoxification of copper ion [ISS]
- dopamine metabolic process [ISS]
- elastic fiber assembly [ISS]
- elastin biosynthetic process [ISS]
- epinephrine metabolic process [ISS]
- extracellular matrix organization [ISS]
- hair follicle morphogenesis [ISS]
- ion transmembrane transport [TAS]
- locomotory behavior [ISS]
- lung alveolus development [ISS]
- mitochondrion organization [ISS]
- negative regulation of metalloenzyme activity [ISS]
- neuron projection morphogenesis [ISS]
- norepinephrine metabolic process [ISS]
- peptidyl-lysine modification [ISS]
- pigmentation [ISS]
- positive regulation of catalytic activity [ISS]
- positive regulation of metalloenzyme activity [ISS]
- positive regulation of oxidoreductase activity [IDA]
- pyramidal neuron development [ISS]
- regulation of oxidative phosphorylation [ISS]
- removal of superoxide radicals [ISS]
- serotonin metabolic process [ISS]
- skin development [ISS]
- transmembrane transport [TAS]
- tryptophan metabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID