BAIT
TMEM216
HSPC244
transmembrane protein 216
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
ANO6
BDPLT7, SCTS, TMEM16F
anoctamin 6
GO Process (12)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- activation of blood coagulation via clotting cascade [IMP]
- blood coagulation [ISS]
- cation transmembrane transport [IDA, ISS]
- cation transport [IDA]
- chloride transmembrane transport [IMP]
- chloride transport [IMP]
- ion transmembrane transport [TAS]
- phosphatidylserine exposure on blood platelet [IMP]
- phospholipid scrambling [ISS]
- positive regulation of endothelial cell apoptotic process [IMP]
- regulation of anion transport [IMP]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID