BAIT
NDUFA11
B14.7, CI-B14.7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
GO Process (3)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFB4
B15, CI-B15
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
GO Process (5)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex.
Complex I (CI) of the electron transport chain, a large membrane-embedded NADH dehydrogenase, couples electron transfer to the release of protons into the mitochondrial inner membrane space to promote ATP production through ATP synthase. In addition to being a central conduit for ATP production, CI activity has been linked to neurodegenerative disorders, including Parkinson's disease. CI is built in a ... [more]
Mol. Cell. Biol. Mar. 01, 2014; 34(5);847-61 [Pubmed: 24344204]
Throughput
- Low Throughput
Curated By
- BioGRID