BAIT
NDUFV1
CI-51K, CI51KD, UQOR1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
GO Process (4)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFB4
B15, CI-B15
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
GO Process (5)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex.
Complex I (CI) of the electron transport chain, a large membrane-embedded NADH dehydrogenase, couples electron transfer to the release of protons into the mitochondrial inner membrane space to promote ATP production through ATP synthase. In addition to being a central conduit for ATP production, CI activity has been linked to neurodegenerative disorders, including Parkinson's disease. CI is built in a ... [more]
Mol. Cell. Biol. Mar. 01, 2014; 34(5);847-61 [Pubmed: 24344204]
Throughput
- Low Throughput
Curated By
- BioGRID