BAIT
LIMA1
EPLIN, SREBP3, PP624
LIM domain and actin binding 1
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DST
BP240, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2, RP3-361I14.2
dystonin
GO Process (9)
GO Function (5)
GO Component (16)
Gene Ontology Biological Process
- cell motility [IMP]
- cytoskeleton organization [IMP]
- extracellular matrix organization [TAS]
- hemidesmosome assembly [IDA]
- integrin-mediated signaling pathway [NAS]
- intermediate filament cytoskeleton organization [IEP, ISS, NAS]
- maintenance of cell polarity [IMP]
- microtubule cytoskeleton organization [IDA]
- response to wounding [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [IDA]
- actin cytoskeleton [IDA]
- axon [IDA]
- basal plasma membrane [NAS]
- basement membrane [TAS]
- cell leading edge [IDA]
- cytoplasm [IDA, ISS]
- cytoplasmic membrane-bounded vesicle [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- hemidesmosome [IDA, TAS]
- intermediate filament cytoskeleton [IDA]
- microtubule cytoskeleton [IDA]
- microtubule plus-end [IDA]
- nucleus [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID