CHMP4B
Gene Ontology Biological Process
- endosomal transport [TAS]
- membrane organization [TAS]
- negative regulation of autophagic vacuole assembly [IMP]
- negative regulation of neuron death [IMP]
- positive regulation of viral release from host cell [IMP]
- posttranslational protein targeting to membrane [IMP]
- protein homooligomerization [IDA]
- regulation of viral process [IMP]
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [IMP]
- viral budding via host ESCRT complex [IGI]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
BST2
Gene Ontology Biological Process
- cell proliferation [TAS]
- cell-cell signaling [TAS]
- defense response to virus [IDA]
- humoral immune response [TAS]
- innate immune response [IDA]
- multicellular organismal development [TAS]
- negative regulation of cell growth [IDA]
- negative regulation of cell migration [IDA]
- negative regulation of endopeptidase activity [IDA]
- negative regulation of intracellular transport of viral material [IDA]
- negative regulation of plasmacytoid dendritic cell cytokine production [IDA]
- negative regulation of viral genome replication [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- regulation of actin cytoskeleton organization [ISS]
- response to interferon-alpha [ISS]
- response to interferon-beta [ISS]
- response to interferon-gamma [ISS]
- response to virus [IDA]
- signal transduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CHMP4B BST2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID