BAIT
TACC1
Ga55
transforming, acidic coiled-coil containing protein 1
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LYST
CHS, CHS1
lysosomal trafficking regulator
GO Process (9)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- defense response to bacterium [ISS]
- defense response to protozoan [ISS]
- defense response to virus [ISS]
- endosome to lysosome transport via multivesicular body sorting pathway [IMP]
- leukocyte chemotaxis [ISS]
- mast cell secretory granule organization [ISS]
- melanosome organization [ISS]
- natural killer cell mediated cytotoxicity [IMP]
- pigmentation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID