BAIT
RPL10
AUTSX5, DXS648, DXS648E, L10, NOV, QM, XX-FW83563B9.1
ribosomal protein L10
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [IC, NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IFI16
IFNGIP1, PYHIN2
interferon, gamma-inducible protein 16
GO Process (24)
GO Function (8)
GO Component (7)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity [IMP]
- activation of innate immune response [IDA]
- cell proliferation [NAS]
- cellular response to glucose starvation [IDA]
- cellular response to ionizing radiation [IDA]
- defense response to virus [IMP]
- hemopoiesis [NAS]
- innate immune response [TAS]
- intrinsic apoptotic signaling pathway by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IDA]
- monocyte differentiation [IDA]
- myeloid cell differentiation [NAS]
- negative regulation of DNA binding [IDA]
- negative regulation of cysteine-type endopeptidase activity [IDA]
- negative regulation of innate immune response [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [IDA]
- negative regulation of viral genome replication [IDA]
- positive regulation of cytokine production [TAS]
- positive regulation of interleukin-1 beta production [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of type I interferon production [TAS]
- regulation of autophagy [IEP]
- regulation of gene expression, epigenetic [IMP]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- core promoter binding [IDA]
- double-stranded DNA binding [IDA]
- identical protein binding [IPI]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- transcription factor binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- core promoter binding [IDA]
- double-stranded DNA binding [IDA]
- identical protein binding [IPI]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- transcription factor binding [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID