BAIT
KLC3
KLC2, KLC2L, KLCt, KNS2B
kinesin light chain 3
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
NFKBIL1
IKBL, LST1, NFKBIL, DADB-70P7.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- I-kappaB kinase/NF-kappaB signaling [IBA]
- cellular response to lipopolysaccharide [IDA]
- cytoplasmic sequestering of transcription factor [TAS]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of lipopolysaccharide-mediated signaling pathway [IDA]
- negative regulation of toll-like receptor signaling pathway [IDA]
- negative regulation of tumor necrosis factor production [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID