BAIT
PARD6B
PAR6B
par-6 family cell polarity regulator beta
GO Process (8)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ROBO2
SAX3
roundabout, axon guidance receptor, homolog 2 (Drosophila)
GO Process (14)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process involved in luteolysis [IEP]
- axon guidance [ISS, TAS]
- axon midline choice point recognition [ISS]
- brain development [IEP]
- cellular response to hormone stimulus [IEP]
- central nervous system development [NAS]
- homophilic cell adhesion via plasma membrane adhesion molecules [IDA]
- metanephros development [ISS]
- negative regulation of negative chemotaxis [IDA]
- negative regulation of synapse assembly [ISS]
- olfactory bulb interneuron development [ISS]
- positive regulation of axonogenesis [IDA]
- retinal ganglion cell axon guidance [ISS]
- ureteric bud development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID