BAIT
AKAP1
AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, TDRD17
A kinase (PRKA) anchor protein 1
GO Process (1)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
TNNI3
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
troponin I type 3 (cardiac)
GO Process (9)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- cardiac muscle contraction [IMP]
- cellular calcium ion homeostasis [ISS]
- heart contraction [IMP]
- heart development [ISS]
- muscle filament sliding [TAS]
- negative regulation of ATPase activity [IDA, IMP]
- regulation of systemic arterial blood pressure by ischemic conditions [ISS]
- vasculogenesis [ISS]
- ventricular cardiac muscle tissue morphogenesis [IMP]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID