BAIT
MSH6
GTBP, GTMBP, HNPCC5, HSAP, p160
mutS homolog 6
GO Process (15)
GO Function (16)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [IBA, IDA]
- DNA repair [IDA]
- determination of adult lifespan [ISS]
- intrinsic apoptotic signaling pathway [ISS]
- intrinsic apoptotic signaling pathway in response to DNA damage [IBA, ISS]
- isotype switching [IBA, ISS]
- maintenance of DNA repeat elements [IMP]
- meiotic mismatch repair [IBA, ISS]
- mismatch repair [IDA, IGI, IMP]
- negative regulation of DNA recombination [IDA]
- positive regulation of helicase activity [IDA]
- reciprocal meiotic recombination [IBA]
- response to UV [IBA, ISS]
- somatic hypermutation of immunoglobulin genes [IBA, ISS]
- somatic recombination of immunoglobulin gene segments [ISS]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [IDA]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- guanine/thymine mispair binding [IDA]
- magnesium ion binding [IDA]
- methylated histone binding [IDA]
- mismatched DNA binding [IDA]
- oxidized purine DNA binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single guanine insertion binding [IDA]
- single thymine insertion binding [IDA]
- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [IDA]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- guanine/thymine mispair binding [IDA]
- magnesium ion binding [IDA]
- methylated histone binding [IDA]
- mismatched DNA binding [IDA]
- oxidized purine DNA binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single guanine insertion binding [IDA]
- single thymine insertion binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
AKR7A2
AFAR, AFAR1, AFB1-AR1, AKR7
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
GO Process (4)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID