FGD1
Gene Ontology Biological Process
- actin cytoskeleton organization [IDA]
- apoptotic signaling pathway [TAS]
- cytoskeleton organization [ISS]
- filopodium assembly [IDA]
- multicellular organismal development [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- organ morphogenesis [TAS]
- positive regulation of GTPase activity [IDA]
- positive regulation of apoptotic process [TAS]
- regulation of Cdc42 GTPase activity [IDA]
- regulation of cell shape [ISS]
- regulation of small GTPase mediated signal transduction [TAS]
- signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SH3PXD2A
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SH3PXD2A FGD1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3059487 | |
| FGD1 SH3PXD2A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 5.3852 | BioGRID | 2844760 |
Curated By
- BioGRID