BAIT
SYNCRIP
GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, RP1-3J17.2
synaptotagmin binding, cytoplasmic RNA interacting protein
GO Process (7)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ABCA7
ABCA-SSN, ABCX
ATP-binding cassette, sub-family A (ABC1), member 7
GO Process (20)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- apolipoprotein A-I-mediated signaling pathway [IDA]
- cholesterol efflux [IDA]
- high-density lipoprotein particle assembly [IDA]
- memory [ISS]
- negative regulation of ATPase activity [IDA]
- negative regulation of amyloid precursor protein biosynthetic process [ISS]
- negative regulation of beta-amyloid formation [ISS]
- peptide cross-linking [ISS]
- phospholipid efflux [IDA]
- phospholipid scrambling [IDA]
- positive regulation of ATPase activity [IDA]
- positive regulation of ERK1 and ERK2 cascade [ISS]
- positive regulation of beta-amyloid clearance [ISS]
- positive regulation of cholesterol efflux [ISS]
- positive regulation of engulfment of apoptotic cell [ISS]
- positive regulation of phagocytosis [ISS]
- positive regulation of phospholipid efflux [ISS]
- protein localization to nucleus [ISS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID