BAIT
SORT1
Gp95, LDLCQ6, NT3
sortilin 1
GO Process (16)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IMP]
- Golgi to endosome transport [IDA]
- endocytosis [IDA]
- endosome to lysosome transport [IDA]
- endosome transport via multivesicular body sorting pathway [IDA]
- extrinsic apoptotic signaling pathway via death domain receptors [IDA]
- glucose import [IMP]
- myotube differentiation [IMP]
- negative regulation of lipoprotein lipase activity [IDA]
- nerve growth factor signaling pathway [IDA]
- neuropeptide signaling pathway [IDA]
- neurotrophin TRK receptor signaling pathway [IMP]
- plasma membrane to endosome transport [IDA]
- regulation of gene expression [IMP]
- response to insulin [IMP]
- vesicle organization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SYNCRIP
GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, RP1-3J17.2
synaptotagmin binding, cytoplasmic RNA interacting protein
GO Process (7)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID