BAIT
NIPSNAP1
nipsnap homolog 1 (C. elegans)
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
HPSE
HPA, HPA1, HPR1, HPSE1, HSE1
heparanase
GO Process (12)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cell-matrix adhesion [IDA]
- glycosaminoglycan catabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- heparan sulfate proteoglycan catabolic process [IDA]
- positive regulation of blood coagulation [IDA]
- positive regulation of osteoblast proliferation [IDA]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation vascular endothelial growth factor production [IDA]
- proteoglycan metabolic process [TAS]
- regulation of hair follicle development [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID