BAIT
NABP2
OBFC2B, SOSS-B1, SSB1, hSSB1, LP3587
nucleic acid binding protein 2
GO Process (5)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
VPS4A
SKD1, SKD1A, SKD2, VPS4, VPS4-1
vacuolar protein sorting 4 homolog A (S. cerevisiae)
GO Process (16)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [NAS]
- abscission [IMP]
- cytokinesis [IDA]
- cytokinesis checkpoint [IMP]
- cytoplasmic microtubule organization [IBA]
- endosomal transport [IMP, TAS]
- membrane organization [TAS]
- negative regulation of cytokinesis [IMP]
- positive regulation of exosomal secretion [IMP]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IMP]
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [IMP]
- vacuole organization [IBA]
- vesicle-mediated transport [IDA]
- viral budding via host ESCRT complex [IGI]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID