BAIT
PRKCI
2310021H13Rik, AI427505, PKClambda, Pkci, Pkcl, Prkcl, aPKClambda, mKIAA4165
protein kinase C, iota
GO Process (19)
GO Function (6)
GO Component (14)
Gene Ontology Biological Process
- Golgi vesicle budding [ISO]
- actin filament organization [IMP]
- cell migration [ISO]
- cell-cell junction organization [ISO]
- cellular protein localization [ISO]
- cellular response to insulin stimulus [IMP, ISO]
- establishment of apical/basal cell polarity [IMP]
- eye photoreceptor cell development [IMP]
- negative regulation of glial cell apoptotic process [ISO]
- negative regulation of neuron apoptotic process [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of endothelial cell apoptotic process [ISO]
- positive regulation of establishment of protein localization to plasma membrane [IMP]
- positive regulation of glial cell proliferation [ISO]
- positive regulation of glucose import [IMP]
- positive regulation of neuron projection development [ISO]
- protein phosphorylation [IDA, ISO]
- response to interleukin-1 [ISO]
- response to peptide hormone [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi membrane [ISO]
- Schmidt-Lanterman incisure [IDA]
- apical part of cell [IDA]
- apical plasma membrane [IDA]
- cell leading edge [ISO]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- intercellular bridge [ISO]
- microtubule cytoskeleton [ISO]
- nucleus [IDA, ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- tight junction [ISO]
Mus musculus
PREY
ALDH3A2
ALDH10, FALDH, SLS
aldehyde dehydrogenase 3 family, member A2
GO Process (7)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID