BAIT
BMPR1A
1110037I22Rik, ALK3, AU045487, BMPR-IA, Bmpr
bone morphogenetic protein receptor, type 1A
GO Process (50)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- BMP signaling pathway [IDA, IGI, IMP, ISO]
- Mullerian duct regression [IMP]
- anterior/posterior pattern specification [IMP]
- cartilage development [IMP]
- cell differentiation [IGI]
- developmental growth [IMP]
- dorsal/ventral axis specification [IMP]
- dorsal/ventral pattern formation [IGI]
- ectoderm development [IMP]
- embryonic digit morphogenesis [IGI]
- embryonic morphogenesis [IMP]
- embryonic organ development [IMP]
- endocardial cushion formation [IMP]
- endoderm development [IMP]
- heart development [IMP]
- heart formation [IMP]
- heart morphogenesis [IMP]
- hindlimb morphogenesis [IMP]
- immune response [ISO]
- in utero embryonic development [IMP]
- lateral mesoderm development [IMP]
- lung development [IMP]
- mesendoderm development [IMP]
- mesoderm formation [IMP]
- negative regulation of neurogenesis [IMP]
- nervous system development [IMP]
- neural crest cell development [IMP]
- neural plate mediolateral regionalization [IMP]
- neural plate pattern specification [IMP]
- odontogenesis of dentin-containing tooth [IMP]
- palate development [IMP]
- paraxial mesoderm development [IGI, IMP]
- paraxial mesoderm structural organization [IMP]
- pattern specification process [IMP]
- pituitary gland development [IMP]
- positive regulation of SMAD protein import into nucleus [ISO]
- positive regulation of bone mineralization [ISO]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [ISO]
- positive regulation of transcription, DNA-templated [IDA]
- protein phosphorylation [ISO]
- regulation of cellular senescence [IGI]
- regulation of endothelial cell differentiation [IDA]
- regulation of endothelial cell proliferation [IDA]
- regulation of lateral mesodermal cell fate specification [IGI]
- somitogenesis [IMP]
- stem cell maintenance [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CD44
CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, AL133330.1
CD44 molecule (Indian blood group)
GO Process (25)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- blood coagulation [TAS]
- carbohydrate metabolic process [TAS]
- cartilage development [IEP]
- cell-matrix adhesion [NAS]
- cellular response to fibroblast growth factor stimulus [IDA]
- cytokine-mediated signaling pathway [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- glycosaminoglycan metabolic process [TAS]
- hyaluronan catabolic process [IDA, TAS]
- hyaluronan metabolic process [TAS]
- interferon-gamma-mediated signaling pathway [TAS]
- leukocyte migration [TAS]
- monocyte aggregation [IMP]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [IDA]
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IDA]
- positive regulation of ERK1 and ERK2 cascade [IDA]
- positive regulation of heterotypic cell-cell adhesion [IMP]
- positive regulation of monocyte aggregation [IMP]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- single organismal cell-cell adhesion [NAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID