BAIT
MYH10
5730504C04Rik, 9330167F11Rik, Fltn, Myhn-2, Myhn2, NMHC II-B, NMHC-B, NMHCII-B, NMMHC II-b, NMMHC-B, NMMHC-IIB, SMemb, mKIAA3005, RP23-396M19.2
myosin, heavy polypeptide 10, non-muscle
GO Process (27)
GO Function (6)
GO Component (21)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- actin cytoskeleton organization [IGI]
- actin filament-based movement [ISO]
- actomyosin structure organization [ISO]
- adult heart development [IMP]
- axon guidance [IMP]
- axonogenesis [IMP]
- brain development [IMP]
- cardiac myofibril assembly [IMP]
- cell proliferation [IMP]
- cerebellar Purkinje cell layer development [IMP]
- exocytosis [IMP]
- fourth ventricle development [IMP]
- in utero embryonic development [IMP]
- lateral ventricle development [IMP]
- mitotic cytokinesis [IMP, ISO]
- myofibril assembly [IMP]
- neuromuscular process controlling balance [IMP]
- neuron migration [IMP]
- neuron projection development [IMP]
- nuclear migration [IMP]
- plasma membrane repair [IMP]
- regulation of cell shape [IMP]
- retina development in camera-type eye [IMP]
- substrate-dependent cell migration, cell extension [IMP]
- third ventricle development [IMP]
- ventricular cardiac muscle cell development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISO]
- actomyosin [ISO]
- axon [IDA]
- cell cortex [IDA, ISO]
- cleavage furrow [ISO]
- cytoplasm [IDA, ISO]
- dendritic spine [IDA]
- extracellular vesicular exosome [ISO]
- growth cone [IDA]
- midbody [ISO]
- mitochondrion [ISO]
- myosin II complex [IDA, ISO]
- myosin II filament [ISO]
- myosin complex [IDA]
- neuromuscular junction [IDA]
- neuron projection [IDA]
- neuronal cell body [IDA]
- nucleus [ISO]
- plasma membrane [IDA]
- spindle [IDA]
- stress fiber [IDA, IMP, ISO]
Mus musculus
PREY
CLTC
CHC, CHC17, CLH-17, CLTCL2, Hc
clathrin, heavy chain (Hc)
GO Process (11)
GO Function (6)
GO Component (15)
Gene Ontology Biological Process
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- intracellular protein transport [NAS]
- membrane organization [TAS]
- mitotic nuclear division [IMP]
- negative regulation of hyaluronan biosynthetic process [IDA, IMP]
- negative regulation of protein localization to plasma membrane [IMP]
- osteoblast differentiation [IDA]
- post-Golgi vesicle-mediated transport [TAS]
- receptor internalization [IMP]
- receptor-mediated endocytosis [IMP]
- transferrin transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- clathrin coat [NAS]
- clathrin complex [IDA]
- clathrin-coated endocytic vesicle membrane [TAS]
- clathrin-coated vesicle [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- intracellular membrane-bounded organelle [IDA]
- membrane [IDA]
- plasma membrane [TAS]
- protein complex [IDA]
- spindle [IDA]
- trans-Golgi network membrane [TAS]
- vesicle [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID