BAIT
FBXW11
2310065A07Rik, AA536858, BTRC2, BTRCP2, Fbxw1b, HOS, RP23-94F11.1
F-box and WD-40 domain protein 11
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IMP, ISO]
- negative regulation of NF-kappaB import into nucleus [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of circadian rhythm [IMP]
- positive regulation of proteolysis [ISO]
- positive regulation of transcription, DNA-templated [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- protein dephosphorylation [IDA]
- protein destabilization [ISO]
- protein polyubiquitination [IDA, ISO]
- protein ubiquitination [ISO]
Gene Ontology Molecular Function
Mus musculus
PREY
HNRNPA2B1
HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1
heterogeneous nuclear ribonucleoprotein A2/B1
GO Process (5)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID