BAIT
MYO1C
C80397, MMIb, MYO1E, NMI, mm1beta, myr2, RP23-136K12.2
myosin IC
GO Process (9)
GO Function (8)
GO Component (15)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [ISO]
- positive regulation of protein targeting to membrane [ISO]
- positive regulation of vascular endothelial growth factor signaling pathway [ISO]
- protein targeting [ISO]
- protein targeting to membrane [ISO]
- regulation of tight junction assembly [ISO]
- transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [ISO]
- brush border [IDA]
- cytoplasm [ISO]
- extracellular vesicular exosome [ISO]
- filamentous actin [ISO]
- lateral plasma membrane [ISO]
- membrane [ISO, TAS]
- membrane raft [ISO]
- microvillus [ISO]
- mitochondrion [ISO]
- myosin I complex [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- stereocilium [IDA]
Mus musculus
PREY
ITPR3
IP3R, IP3R3
inositol 1,4,5-trisphosphate receptor, type 3
GO Process (20)
GO Function (6)
GO Component (13)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- G-protein coupled receptor signaling pathway [ISS]
- activation of phospholipase C activity [TAS]
- blood coagulation [TAS]
- calcium ion transport into cytosol [ISS]
- energy reserve metabolic process [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- inositol phosphate-mediated signaling [IDA, ISS]
- neurotrophin TRK receptor signaling pathway [TAS]
- platelet activation [TAS]
- positive regulation of cytosolic calcium ion concentration [ISS]
- protein heterooligomerization [ISS]
- protein homooligomerization [ISS]
- regulation of insulin secretion [TAS]
- response to calcium ion [IDA]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical part of cell [ISS]
- brush border [ISS]
- cytoplasm [ISS]
- endoplasmic reticulum [ISS]
- endoplasmic reticulum membrane [IDA, ISS, TAS]
- integral component of plasma membrane [IDA]
- membrane [IDA]
- myelin sheath [ISS]
- neuronal cell body [ISS]
- nuclear outer membrane [ISS]
- plasma membrane [IDA]
- platelet dense tubular network membrane [TAS]
- receptor complex [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID