BAIT
TMED10
1110014C03Rik, Tmp21, p23, p24delta1
transmembrane emp24-like trafficking protein 10 (yeast)
GO Process (5)
GO Function (2)
GO Component (15)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- COPI-coated vesicle [ISO]
- Golgi apparatus [ISO]
- Golgi membrane [ISO]
- cell [TAS]
- cis-Golgi network [ISO, ISS]
- endoplasmic reticulum [ISO]
- endoplasmic reticulum-Golgi intermediate compartment [ISO]
- extracellular vesicular exosome [ISO]
- gamma-secretase complex [ISO]
- integral component of membrane [ISO]
- intracellular [TAS]
- intracellular membrane-bounded organelle [ISO]
- plasma membrane [ISO]
- secretory granule membrane [IDA]
- zymogen granule membrane [IDA, ISO]
Mus musculus
PREY
MYO1C
MMI-beta, MMIb, NMI, myr2
myosin IC
GO Process (10)
GO Function (2)
GO Component (14)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- innate immune response [TAS]
- membrane organization [TAS]
- positive regulation of cell migration [IMP]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [IMP]
- positive regulation of protein targeting to membrane [IMP]
- positive regulation of vascular endothelial growth factor signaling pathway [IMP]
- protein targeting [IDA]
- protein targeting to membrane [IDA]
- regulation of tight junction assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- filamentous actin [IDA]
- lateral plasma membrane [IDA]
- membrane [IDA]
- membrane raft [IDA]
- microvillus [IDA]
- mitochondrion [IDA]
- nucleoplasm [IDA]
- plasma membrane [IDA]
- stress fiber [IDA]
- unconventional myosin complex [TAS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID