BAIT
RACGAP1
AI227039, AI327394, Band25, GTPase, MgcRacGAP, gtl11, mKIAA1478
Rac GTPase-activating protein 1
GO Process (9)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
- actomyosin contractile ring assembly [ISO]
- cytokinesis, initiation of separation [ISO]
- embryo development [IMP]
- mitotic cytokinesis [ISO]
- mitotic spindle midzone assembly [ISO]
- positive regulation of GTPase activity [ISO]
- positive regulation of cytokinesis [ISO]
- regulation of attachment of spindle microtubules to kinetochore [ISO]
- sulfate transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NRAS
ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6, RP5-1000E10.2
neuroblastoma RAS viral (v-ras) oncogene homolog
GO Process (13)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- MAPK cascade [TAS]
- Ras protein signal transduction [TAS]
- activation of MAPKK activity [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- leukocyte migration [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID