BAIT
PRKACB
Pkacb
protein kinase, cAMP dependent, catalytic, beta
GO Process (6)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- adenylate cyclase-modulating G-protein coupled receptor signaling pathway [TAS]
- negative regulation of meiotic cell cycle [ISO]
- negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [IGI]
- neural tube closure [IGI]
- protein phosphorylation [IDA, ISO]
- regulation of protein processing [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PCM1
PTC4
pericentriolar material 1
GO Process (11)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- centrosome organization [IMP]
- cilium assembly [IMP]
- cytoplasmic microtubule organization [IMP]
- interkinetic nuclear migration [ISS]
- intraciliary transport involved in cilium morphogenesis [IMP]
- microtubule anchoring [ISS]
- mitotic cell cycle [TAS]
- negative regulation of neurogenesis [ISS]
- positive regulation of intracellular protein transport [IMP]
- protein localization to centrosome [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID