BAIT
RHOA
Arha, Arha1, Arha2
ras homolog gene family, member A
GO Process (44)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
- GTP catabolic process [IDA, ISO]
- Rho protein signal transduction [TAS]
- actin cytoskeleton organization [IDA]
- androgen receptor signaling pathway [IDA]
- apical junction assembly [IDA, ISO]
- apolipoprotein A-I-mediated signaling pathway [ISO]
- cell adhesion [IMP]
- cell differentiation [IDA]
- cell morphogenesis [IGI]
- cell-matrix adhesion [IDA]
- cerebral cortex cell migration [IMP]
- cleavage furrow formation [ISO]
- cytoskeleton organization [IMP]
- forebrain radial glial cell differentiation [IMP]
- integrin-mediated signaling pathway [TAS]
- negative chemotaxis [ISO]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of cell death [ISO]
- negative regulation of intracellular steroid hormone receptor signaling pathway [IDA]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of neuron differentiation [ISO]
- ossification involved in bone maturation [IMP]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of neuron apoptotic process [ISO]
- positive regulation of neuron differentiation [ISO]
- positive regulation of podosome assembly [IGI]
- positive regulation of smooth muscle contraction [ISO]
- positive regulation of stress fiber assembly [ISO]
- regulation of calcium ion transport [ISO]
- regulation of cell migration [ISO]
- regulation of dendrite development [ISO]
- regulation of neural precursor cell proliferation [IMP]
- regulation of neuron projection development [IDA]
- regulation of osteoblast proliferation [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to drug [ISO]
- skeletal muscle tissue development [IDA]
- spindle assembly involved in mitosis [ISO]
- stress fiber assembly [IDA]
- stress-activated protein kinase signaling cascade [ISO]
- trabecula morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PPL
periplakin
GO Process (0)
GO Function (2)
GO Component (1)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID