BAIT
PPP2R1A
6330556D22Rik, PP2A, PR65
protein phosphatase 2, regulatory subunit A, alpha
GO Process (3)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PPP2R3A
PPP2R3, PR130, PR72
protein phosphatase 2, regulatory subunit B'', alpha
GO Process (10)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- Wnt signaling pathway involved in somitogenesis [IC]
- eye photoreceptor cell differentiation [IGI]
- negative regulation of canonical Wnt signaling pathway [IGI]
- positive regulation of canonical Wnt signaling pathway [IDA]
- positive regulation of protein catabolic process [IMP]
- protein dephosphorylation [ISS]
- regulation of catalytic activity [TAS]
- regulation of cell motility involved in somitogenic axis elongation [IGI]
- somatic muscle development [IGI]
- somite development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID