BAIT
PAFAH1B1
LIS-1, Lis1, MMS10-U, Mdsh, Ms10u, Pafaha, RP23-194P5.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
GO Process (35)
GO Function (7)
GO Component (22)
Gene Ontology Biological Process
- acrosome assembly [IMP]
- actin cytoskeleton organization [IMP]
- adult locomotory behavior [IMP, ISO]
- ameboidal-type cell migration [IMP]
- brain morphogenesis [ISO]
- cell migration [IMP]
- cerebral cortex development [IGI, IMP, ISO]
- cerebral cortex neuron differentiation [ISO]
- corpus callosum morphogenesis [ISO]
- establishment of centrosome localization [ISO]
- establishment of mitotic spindle orientation [ISO]
- hippocampus development [IGI, IMP]
- layer formation in cerebral cortex [IGI]
- learning or memory [IMP]
- microtubule cytoskeleton organization [IGI, IMP]
- microtubule organizing center organization [ISO]
- microtubule-based process [ISO]
- negative regulation of JNK cascade [IGI]
- negative regulation of neuron projection development [ISO]
- neuroblast proliferation [IMP]
- neuromuscular process controlling balance [IMP, ISO]
- neuron migration [IGI, IMP, ISO]
- nuclear envelope disassembly [IMP]
- nuclear migration [ISO]
- osteoclast development [IMP]
- positive regulation of axon extension [ISO]
- positive regulation of cytokine-mediated signaling pathway [IMP]
- positive regulation of mitotic cell cycle [ISO]
- protein secretion [IMP]
- regulation of Rho GTPase activity [IMP]
- retrograde axon cargo transport [IDA]
- stem cell division [ISO]
- synaptic transmission [IMP]
- transmission of nerve impulse [IMP]
- vesicle transport along microtubule [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- astral microtubule [ISO]
- axon [ISO]
- cell [IGI]
- cell cortex [ISO]
- cell leading edge [IDA]
- centrosome [IDA, ISO]
- cytoplasm [IDA]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- intracellular [IGI]
- kinesin complex [ISO]
- kinetochore [ISO]
- microtubule associated complex [IDA, ISO]
- microtubule cytoskeleton [IDA]
- motile primary cilium [IDA]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nonmotile primary cilium [IDA]
- nuclear envelope [ISO, ISS]
- perinuclear region of cytoplasm [IDA]
- vesicle [ISO]
Mus musculus
PREY
PSMA5
PSC5, ZETA
proteasome (prosome, macropain) subunit, alpha type, 5
GO Process (21)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [TAS]
- G1/S transition of mitotic cell cycle [TAS]
- RNA metabolic process [TAS]
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- apoptotic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- negative regulation of apoptotic process [TAS]
- negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- protein polyubiquitination [TAS]
- regulation of apoptotic process [TAS]
- regulation of cellular amino acid metabolic process [TAS]
- regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- small molecule metabolic process [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID