BAIT
ECT2
AI528536, mKIAA4037
ect2 oncogene
GO Process (20)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- activation of Rac GTPase activity [ISO]
- activation of Rho GTPase activity [ISO]
- activation of protein kinase activity [ISO]
- cell morphogenesis [IDA]
- cellular response to calcium ion [ISO]
- cellular response to hydrogen peroxide [ISO]
- cellular response to ionizing radiation [ISO]
- cytokinesis [ISO]
- positive regulation of Cdc42 GTPase activity [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of Rho GTPase activity [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of neuron differentiation [IMP]
- positive regulation of protein import into nucleus [IDA]
- protein homooligomerization [ISO]
- regulation of attachment of spindle microtubules to kinetochore [ISO]
- regulation of protein kinase activity [ISO]
- signal transduction [ISO]
- tight junction assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RPL10
AUTSX5, DXS648, DXS648E, L10, NOV, QM, XX-FW83563B9.1
ribosomal protein L10
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [IC, NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID