BAIT
TNKS
4930554K12Rik, AI662855, ARTD5, C86528, D130072O21Rik, TANK1, mTNKS1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- negative regulation of DNA binding [ISO]
- peptidyl-serine phosphorylation [ISO]
- peptidyl-threonine phosphorylation [ISO]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of telomere maintenance via telomerase [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- protein ADP-ribosylation [ISO]
- protein auto-ADP-ribosylation [ISO]
- protein localization to chromosome, telomeric region [ISO]
- protein poly-ADP-ribosylation [ISO]
- protein polyubiquitination [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SDC2
CD362, HSPG, HSPG1, SYND2
syndecan 2
GO Process (10)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- chondroitin sulfate metabolic process [TAS]
- extracellular matrix organization [TAS]
- glycosaminoglycan biosynthetic process [TAS]
- glycosaminoglycan catabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- phototransduction, visible light [TAS]
- regulation of dendrite morphogenesis [ISS]
- retinoid metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID