BAIT
SESN2
HI95, SEST2, Ses2, RP23-63D8.3
sestrin 2
GO Process (13)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
- autophagy [IMP]
- fatty acid beta-oxidation [IGI]
- glucose homeostasis [IGI]
- glucose import [IMP]
- mitochondrial DNA metabolic process [IMP]
- mitochondrion organization [IMP]
- protein kinase B signaling [IMP]
- regulation of cAMP-dependent protein kinase activity [IMP]
- regulation of gluconeogenesis involved in cellular glucose homeostasis [IMP]
- regulation of protein phosphorylation [IMP]
- response to glucose [IGI, IMP]
- response to insulin [IGI, IMP]
- triglyceride homeostasis [IMP]
Gene Ontology Cellular Component
Mus musculus
PREY
SEC13
D3S1231E, SEC13L1, SEC13R, npp-20
SEC13 homolog (S. cerevisiae)
GO Process (10)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
- COPII vesicle coating [TAS]
- ER to Golgi vesicle-mediated transport [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cellular protein metabolic process [TAS]
- intracellular protein transport [NAS]
- membrane organization [TAS]
- mitotic cell cycle [TAS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID