BAIT
MYO1C
C80397, MMIb, MYO1E, NMI, mm1beta, myr2, RP23-136K12.2
myosin IC
GO Process (9)
GO Function (8)
GO Component (15)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [ISO]
- positive regulation of protein targeting to membrane [ISO]
- positive regulation of vascular endothelial growth factor signaling pathway [ISO]
- protein targeting [ISO]
- protein targeting to membrane [ISO]
- regulation of tight junction assembly [ISO]
- transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [ISO]
- brush border [IDA]
- cytoplasm [ISO]
- extracellular vesicular exosome [ISO]
- filamentous actin [ISO]
- lateral plasma membrane [ISO]
- membrane [ISO, TAS]
- membrane raft [ISO]
- microvillus [ISO]
- mitochondrion [ISO]
- myosin I complex [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- stereocilium [IDA]
Mus musculus
PREY
ST5
DENND2B, HTS1, p126
suppression of tumorigenicity 5
GO Process (2)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID