BAIT
DCTN3
p24
dynactin 3
GO Process (2)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
PREY
TAF6
MGC:8964, TAF(II)70, TAF(II)80, TAF2E, TAFII-70, TAFII-80, TAFII70, TAFII80, TAFII85
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
GO Process (9)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- DNA-templated transcription, initiation [IDA]
- gene expression [TAS]
- negative regulation of cell cycle [IDA]
- negative regulation of cell proliferation [IDA]
- regulation of transcription, DNA-templated [IDA]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [NAS, TAS]
- transcription initiation from RNA polymerase II promoter [IDA, TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID